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The effect of LR and BR on production of intracellular metabolites of TCA cycle. Concentrations of metabolic intermediates were measured in cells (HepG2, MRC5, SH-SY5Y) treated for 24 h with LR and BR (5 and 25 μmol/L). *, p < 0.05; #, p < 0.001. 2HG, 2-hydroxyglutarate; 2OG, 2-oxoglutarate; CTRL, control cells. n = 9 for each experiment.
