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Stability of LR and BR. Stability of LR and BR (cLR/BR = 10 μmol/L) was determined during 6 h in: (A) MEM medium spiked with LR and BR (n = 9); (B) human serum spiked with LR and BR (n = 9); (C) different solubilization media spiked with LR (n = 9); (D) MEM medium spiked with LR under hypoxic and normoxic conditions (n = 9); (E) ionizable degradation products of LR screened after 24 h of normoxic incubation in PBS (n = 1). BR, bilirubin; LR, lumirubin.
