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. 2021 Mar 4;12:567001. doi: 10.3389/fphar.2021.567001

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Copyright © 2021 Dvořák, Pospíšilová, Žížalová, Capková, Muchová, Vecka, Vrzáčková, Křížová, Zelenka and Vítek.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Antioxidant potential of LR and BR in vitro. (A) antioxidant capacity (AOX) in human serum spiked with LR and BR (n = 15); (B) AOX of HSA spiked with Trolox, LR and BR (n = 15); (C) AOX of LR in HSA after its spontaneous degradation (initial LR concentration = 25 μmol/L) (n = 6); (D) lipoperoxidation (LPX) of brain tissue after addition of LR (dissolved in PBS) and BR (dissolved in DMSO) (n = 8); (E) LPX of brain tissue after addition of LR and BR dissolved in BSA (n = 8). *, p < 0.05; #, p < 0.001. LR, lumirubin; BR, bilirubin.