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. 2021 Mar 4;8:656086. doi: 10.3389/fmed.2021.656086

Figure 1.

Figure 1

Quercetin protected glomerular MCs from GF-induced inflammation and apoptosis injuries. (A) Viability of MCs was tested by CCK8 at 24, 48, and 72 h. (B) Inflammation levels of TNFα and IL-1β at 24, 48, and 72 h. (C) Apoptosis index was detected by flow cytometry under different glucose at 48 h. (D) Rates of cleaved caspase-3/caspase-3 measured by WB analysis at 48 h. (E,F) Moderate (20 μmol/L) and high dose (40 μmol/L) of quercetin treatment presented protection effects on viability of MCs and levels of inflammation damage. (G,H) Effects of quercetin on apoptosis index and caspase-3 activity. The error bar reflects the S.E.M. of at least three independent experiments. *P < 0.05 vs. NG. #P < 0.05 vs. HG.