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. 2021 Mar 4;12:609406. doi: 10.3389/fimmu.2021.609406

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Copyright © 2021 Santopaolo, Sullivan, Thomas, Alvino, Nicholson, Gu, Spinetti, Kallikourdis, Blom and Madeddu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Altered chemokine profile in BM of patients with T2D. (A) Spider graph showing the expression levels of chemokines, cytokines, and proteins measured using a proteome profiling array in bone marrow perfusates of three subjects per group. Pink line (T2D) and the blue line (ND). (B) The network of factors found to be differentially regulated between T2D and ND. The bar halo color is based on the rank of the protein in the set of input values. Action types are shown as: .

Inline graphic — Altered chemokine profile in BM of patients with T2D. (A) Spider graph showing the expression levels of chemokines, cytokines, and proteins measured using a proteome profiling array in bone marrow perfusates of three subjects per group. Pink line (T2D) and the blue line (ND). (B) The network of factors found to be differentially regulated between T2D and ND. The bar halo color is based on the rank of the protein in the set of input values. Action types are shown as: .