Table 3.
Risk factors for significant intrafractional movement in pediatric patients.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| BMI* | 0.83 (0.64–1.08) | 0.162 | ||
| Total CSI dose* | 1.00 (1.00–1.00) | 0.156 | ||
| Beam on time (< 8 min vs. ≥ 8 min) | 1.42 (0.21–9.55) | 0.721 | ||
| Concurrent chemotherapy (No vs. Yes) | 6.21 × 108 (0.00–0.00) | 0.998 | ||
| Overall CSI treatment time (< 24 days vs. ≥ 24 days) | 0.71 (0.11–4.76) | 0.721 | ||
| Sedation during treatment (No vs. Yes) | 0.00 (0.00–0.00) | 0.999 | ||
| Medically-indicated treatment interruptions (No vs. Yes) | 0.42 (0.04–4.20) | 0.463 | ||
| Weight loss (Grade < 1 vs. Grade ≥ 1) | 11.63 (1.47–92.14) | 0.020 | 11.63 (1.47–92.14) | 0.020 |
| Nausea (Grade < 2 vs. Grade ≥ 2) | 1.93 (0.28–13.44) | 0.509 | ||
OR odds ratio; CI confidence interval; BMI body-mass index; CSI craniospinal irradiation.
*BMI and total CSI dose was treated as a continuous variable.
The foreparts of the parentheses were set as the reference groups in the multivariable analysis.