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. 2021 Mar 15;8(1):e001472. doi: 10.1136/openhrt-2020-001472

Table 5.

Comorbidities, medication and in-hospital outcomes according to myocardial injury

All (N=498) Myocardial injury (N=215) No myocardial injury (N=283) P value
Comorbidities
Cardiovascular disease 319 (64.1%) 164 (76.3%) 155 (54.8%) <0.001
Diabetes 200 (40.2%) 96 (44.7%) 104 (36.7%) 0.08
Hypertension 266 (53.4%) 138 (64.2%) 128 (45.2%) <0.001
Dyslipidaemia 158 (31.7%) 66 (30.7%) 92 (32.5%) 0.698
COPD 34 (6.8%) 15 (7.0%) 19 (6.7%) 0.908
Asthma 45 (9.0%) 18 (8.4%) 27 (9.5%) 0.753
Chronic Kidney Disease 98 (19.7%) 73 (34.0%) 25 (8.8%) <0.001
ESRF on Dialysis 37 (7.4%) 35 (16.3%) 2 (0.7%) <0.001
Coronary artery disease 69 (13.9%) 40 (18.6%) 29 (10.2%) 0.009
Previous MI 45 (9.0%) 30 (14.0%) 15 (5.3%) 0.001
Previous CABG 11 (2.2%) 5 (2.3%) 6 (2.1%) 0.877
Atrial fibrillation 65 (13.1%) 41 (19.1%) 24 (8.5%) 0.001
Previous PCI 27 (5.4%) 17 (7.9%) 10 (3.5%) 0.044
Previous CVA 59 (11.8%) 31 (14.4%) 28 (9.9%) 0.126
Medications
ARB 52 (10.4%) 31 (14.4%) 21 (7.4%) 0.017
ACEi 100 (20.1%) 52 (24.2%) 48 (17.0%) 0.055
Outcomes
Admission to ICU 73 (16.7%) 40 (18.6%) 33 (11.7%) 0.04
 Intubation 58 (11.6%) 30 (14.0%) 28 (9.9%) 0.352
Renal replacement therapy 25 (5.0%) 23 (10.7%) 2 (0.7%) <0.001
Stroke 8 (1.6%) 4 (1.9%) 4 (1.4%) 0.731
Death 154 (30.9%) 102 (47.4%) 52 (18.4%) <0.001

ACEi, ACE inhibitor; ARB, angiotensin receptor blocker; CABG, coronary artery bypass grafting; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; ESRF, end-stage renal failure; ICU, intensive care unit; MI, myocardial infarction; PCI, percutaneous coronary intervention.