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. 2021 Mar 4;9:652972. doi: 10.3389/fcell.2021.652972

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Copyright © 2021 Zhao, Wang, Qu, Zhao, Wang, Ke, Liu, Lei, Liu, Hu, Wei and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OGP46 has anti- proliferation of HL-60, NB4, and Kasumi-1 cells. (A) OGP46’s chemical structure. (B) The cell proliferation effect of OGP46 on the AML cells (HL-60, NB4, and Kasumi-1) cell. Cells were treated with OGP46, ATRA, or Ara-C (0.01–10 μM) for 96 h and then determined by CCK-8 assay. The points represent the mean and error bars represent standard error from three independent triplicate experiments.