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OGP46 induced the apoptosis of HL-60, NB4, and Kasumi-1 cells. (A) HL-60, NB4, and Kasumi-1 cell lines were treated with OGP46 (0.5, 1, 2, or 4 μM), ATRA (1 or 2 μM), or Ara-C (1 μM) for 96 h. Cells were then stained with Annexin V-FITC/PI and detected by flow cytometry. (B) A bar graph showing the statistical analysis of apoptosis (*p < 0.05 and **p < 0.01).
