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. 2021 Mar 4;9:652972. doi: 10.3389/fcell.2021.652972

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Copyright © 2021 Zhao, Wang, Qu, Zhao, Wang, Ke, Liu, Lei, Liu, Hu, Wei and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OGP46 promoted cell differentiation of HL-60, NB4, and Kasumi-1 cells. (A) Morphological pictures of HL-60, NB4, and Kasumi-1 cell lines were captured by oil immersion lens (×1000). (B,C) The expression of cell surface antigens in HL-60, NB4, and Kasumi-1 cells treated with 1, 2, or 1 μM OGP46, respectively, ATRA (1 μM), or Ara-C (1 μM) for 96 h. (B) Mean fluorescence intensity (MFI) of antigens. (C) A bar graph showing the statistical analysis of MFI (*p < 0.05 and **p < 0.01).