FIGURE 3.

Predictive Modeling of Autoimmune Disease. Area under the curve (AUC) (A,C) and F1-scores (B,D) for models predicting any autoimmune disease, inflammatory bowel disease (IBD), multiple sclerosis (MS) and rheumatoid arthritis (RA) for four machine learning models, random forest, XGBoost, support vector machine with recursive feature elimination (SVM RFE) and ridge regression and at the genus and species level. Adult-only (18 years and older) and All (adult + children) models are included for general autoimmunity and IBD studies.