TABLE 8.
A monomer compound derived from a natural drug that modulated ionotropic GABA receptors.
| Compound | Structure | Application | References |
|---|---|---|---|
| Malvidin |
|
Osteoarthritis, Premature senescence, Myocardial infarction | Johnston (2015) |
| Taxifolin |
|
Osteoclastogenesis, Antioxidant, Alzheimer’s disease, hyperuricemic | Johnston (2015) |
| Agathisflavone |
|
Protecting nerve; anti-oxidative damage and anti-viral | Shrestha et al. (2012) |
| 2-Ethyl-7-hydroxy-3′,4′-methylenedioxy-6-propylisoflavone |
|
Unclear | Hanrahan et al. (2015) |
| Glabrol |
|
Antibacterial | Hanrahan et al. (2015) |
| Glabridin |
|
Muscle atrophy, Cardiovascular | Hanrahan et al. (2015) |
| 6-methoxyflavone |
|
Neuropathic allodynia and hypoalgesia, anti-inflammatory | Hall et al. (2014) |
| Vicenin |
|
Prostate cancer, vascular inflammation, Radiation protection | Oliveira et al. (2018) |
| Isovitexin |
|
Various activities, such as anti-oxidant [12], anti-inflammatory, anti-AD effects | Oliveira et al. (2018) |
| Isoliquiritigenin |
|
Cervical cancer, breast cancer, hepatoma cancer, colon cancer, prostate cancer, human leukemia, oral carcinoma, Cardioprotective, Hepatoprotective, Antiangiogenic, anti-microbial, anti-anorexia | Wasowski and Marder (2012) |
| Dihydromyricetin |
|
Antioxidant, anti-inflammatory, protecting cells, regulating lipid and glucose metabolism | Wasowski and Marder (2012) |
| Eriodictyol |
|
Antioxidant, anti-inflammatory, anti-cancer, neuroprotective, cardioprotective, anti-diabetic, anti-obesity, hepatoprotective, and miscellaneous | Wasowski and Marder (2012) |
| Hesperetin |
|
Cancer, anti-inflammatory, cataracts, antioxidant and anti-inflammatory | Wasowski and Marder (2012) |
| 6-methylflavanone |
|
Antioxidant and anticancer | Wasowski and Marder (2012) |
| 3,7-Dihydroxyisoflavan |
|
Anti-oxidant, anti-estrogenic, anti-cancerous and anti-inflammatory | Wasowski and Marder (2012) |
| Oroxylin A |
|
Anti-cancer, antiinflammation, neuroprotective, anti-coagulation | Wasowski and Marder (2012) |
| 2,5,7,-trihydroxy-6,8-dimethoxyflavone |
|
Antioxidant | Wasowski and Marder (2012) |
| 6-methylapigenin |
|
Sedative, sleep-enhancing properties, anxiolytic | Nilsson and Sterner (2011) |
| Skrofulein |
|
Anti-proliferative, anti-cancer, anti-inflammatory, breast cancer, antioxidative and antiplatelet | Nilsson and Sterner (2011) |
| Daidzein |
|
Against various neuropathological conditions mainly by its interaction with the cerebrovascular system, anti-tumor, inhibits choriocarcinoma proliferation | Nilsson and Sterner (2011) |
| Honokiol |
|
Antioxidant, alzheimer, anticancer, antineoplastic, anti-inflammatory | Nilsson and Sterner (2011) |
| Magnolol |
|
Anti-inflammatory, inflammatory bowel disease, Lung cancer, Hepatocellular carcinoma, Antidepressant | Nilsson and Sterner (2011) |
| Miltirone |
|
Antileukemic, anti-inflammatory, anti-platelet, resistant lung cancer | Nilsson and Sterner (2011) |
| Rhusflavone |
|
Inducing sleep | Shen et al. (2016) |
| Galdosol |
|
Antioxidant, Cytostatic and antibacterial | Nilsson and Sterner (2011) |
| Carnosic acid |
|
Antioxidant, anti-inflammatory, anticancer activities, antimicrobial, protecting mitochondria | Nilsson and Sterner (2011) |
| Carnosol |
|
Anti-carcinogenic, atopic dermatitis, gastric tumor, chronic stress, improved lifespan, healthspan | Nilsson and Sterner (2011) |
| Valerenic acid |
|
Anxiety, sleep disturbances, postpartum blues, depression, anti-inflammatory | Nilsson and Sterner (2011) |
| Valeranone |
|
Sedative, tranquilizing antihypertensive properties, hyperkinetic behavior disorders | Nilsson and Sterner (2011) |
| Valtrate |
|
Breast cancer, ovarian cancer, anti-HIV | Nilsson and Sterner (2011) |
| Baldrinal |
|
Anticonvulsant effects | Nilsson and Sterner (2011) |
| (-)-α-thujone |
|
Polycystic ovary syndrome, malignant glioblastoma, Pro-apoptotic and anti-angiogenic | Nilsson and Sterner (2011) |
| Thymol |
|
Antibacterial, antifungal, anticancer, Dermanyssus gallinae, anthelmintic, antioxidant, against geotrichum citri-aurantii | Nilsson and Sterner (2011) |
| Bilobalide |
|
Gastric ulcer, abates inflammation, insulin resistance and secretion of angiogenic factors, alleviates depression | Nilsson and Sterner (2011) |
| Ginkgolide B |
|
Ischemic stroke, anti-inflammatory and chondroprotective | Nilsson and Sterner (2011) |
| Isocurcumenol |
|
Antitumour, anti-androgenic | Nilsson and Sterner (2011) |
| 6-hydroxyflavone |
|
Anxiolytic | Ren et al. (2010) |