TABLE 8.
A monomer compound derived from a natural drug that modulated ionotropic GABA receptors.
Compound | Structure | Application | References |
---|---|---|---|
Malvidin |
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Osteoarthritis, Premature senescence, Myocardial infarction | Johnston (2015) |
Taxifolin |
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Osteoclastogenesis, Antioxidant, Alzheimer’s disease, hyperuricemic | Johnston (2015) |
Agathisflavone |
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Protecting nerve; anti-oxidative damage and anti-viral | Shrestha et al. (2012) |
2-Ethyl-7-hydroxy-3′,4′-methylenedioxy-6-propylisoflavone |
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Unclear | Hanrahan et al. (2015) |
Glabrol |
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Antibacterial | Hanrahan et al. (2015) |
Glabridin |
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Muscle atrophy, Cardiovascular | Hanrahan et al. (2015) |
6-methoxyflavone |
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Neuropathic allodynia and hypoalgesia, anti-inflammatory | Hall et al. (2014) |
Vicenin |
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Prostate cancer, vascular inflammation, Radiation protection | Oliveira et al. (2018) |
Isovitexin |
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Various activities, such as anti-oxidant [12], anti-inflammatory, anti-AD effects | Oliveira et al. (2018) |
Isoliquiritigenin |
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Cervical cancer, breast cancer, hepatoma cancer, colon cancer, prostate cancer, human leukemia, oral carcinoma, Cardioprotective, Hepatoprotective, Antiangiogenic, anti-microbial, anti-anorexia | Wasowski and Marder (2012) |
Dihydromyricetin |
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Antioxidant, anti-inflammatory, protecting cells, regulating lipid and glucose metabolism | Wasowski and Marder (2012) |
Eriodictyol |
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Antioxidant, anti-inflammatory, anti-cancer, neuroprotective, cardioprotective, anti-diabetic, anti-obesity, hepatoprotective, and miscellaneous | Wasowski and Marder (2012) |
Hesperetin |
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Cancer, anti-inflammatory, cataracts, antioxidant and anti-inflammatory | Wasowski and Marder (2012) |
6-methylflavanone |
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Antioxidant and anticancer | Wasowski and Marder (2012) |
3,7-Dihydroxyisoflavan |
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Anti-oxidant, anti-estrogenic, anti-cancerous and anti-inflammatory | Wasowski and Marder (2012) |
Oroxylin A |
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Anti-cancer, antiinflammation, neuroprotective, anti-coagulation | Wasowski and Marder (2012) |
2,5,7,-trihydroxy-6,8-dimethoxyflavone |
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Antioxidant | Wasowski and Marder (2012) |
6-methylapigenin |
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Sedative, sleep-enhancing properties, anxiolytic | Nilsson and Sterner (2011) |
Skrofulein |
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Anti-proliferative, anti-cancer, anti-inflammatory, breast cancer, antioxidative and antiplatelet | Nilsson and Sterner (2011) |
Daidzein |
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Against various neuropathological conditions mainly by its interaction with the cerebrovascular system, anti-tumor, inhibits choriocarcinoma proliferation | Nilsson and Sterner (2011) |
Honokiol |
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Antioxidant, alzheimer, anticancer, antineoplastic, anti-inflammatory | Nilsson and Sterner (2011) |
Magnolol |
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Anti-inflammatory, inflammatory bowel disease, Lung cancer, Hepatocellular carcinoma, Antidepressant | Nilsson and Sterner (2011) |
Miltirone |
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Antileukemic, anti-inflammatory, anti-platelet, resistant lung cancer | Nilsson and Sterner (2011) |
Rhusflavone |
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Inducing sleep | Shen et al. (2016) |
Galdosol |
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Antioxidant, Cytostatic and antibacterial | Nilsson and Sterner (2011) |
Carnosic acid |
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Antioxidant, anti-inflammatory, anticancer activities, antimicrobial, protecting mitochondria | Nilsson and Sterner (2011) |
Carnosol |
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Anti-carcinogenic, atopic dermatitis, gastric tumor, chronic stress, improved lifespan, healthspan | Nilsson and Sterner (2011) |
Valerenic acid |
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Anxiety, sleep disturbances, postpartum blues, depression, anti-inflammatory | Nilsson and Sterner (2011) |
Valeranone |
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Sedative, tranquilizing antihypertensive properties, hyperkinetic behavior disorders | Nilsson and Sterner (2011) |
Valtrate |
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Breast cancer, ovarian cancer, anti-HIV | Nilsson and Sterner (2011) |
Baldrinal |
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Anticonvulsant effects | Nilsson and Sterner (2011) |
(-)-α-thujone |
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Polycystic ovary syndrome, malignant glioblastoma, Pro-apoptotic and anti-angiogenic | Nilsson and Sterner (2011) |
Thymol |
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Antibacterial, antifungal, anticancer, Dermanyssus gallinae, anthelmintic, antioxidant, against geotrichum citri-aurantii | Nilsson and Sterner (2011) |
Bilobalide |
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Gastric ulcer, abates inflammation, insulin resistance and secretion of angiogenic factors, alleviates depression | Nilsson and Sterner (2011) |
Ginkgolide B |
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Ischemic stroke, anti-inflammatory and chondroprotective | Nilsson and Sterner (2011) |
Isocurcumenol |
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Antitumour, anti-androgenic | Nilsson and Sterner (2011) |
6-hydroxyflavone |
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Anxiolytic | Ren et al. (2010) |