Figure 2.

(A) Estimated transcript abundance in different cell lines, ordered by organ of phenotypic resemblance, showing that PRRT2 is mostly expressed in brain cell lines. (B) PRRT2 RNA expression levels in 10 brain areas obtained by combining data from two transcriptomics dataset (GTEx and FANTOM5), showing that PRRT2 is highly expressed in the cerebellum, cerebral cortex, and basal ganglia. (C) Subcellular location of PRRT2 obtained in AF22 cell line by indirect immunofluorescence microscopy (i.e., an antibody-based protein-visualization technique, in which nucleus is stained in blue, microtubules in red and the protein of interest in green) showing that PRRT2 localizes to the plasma membrane, as depicted in the cartoon. NX = consensus normalized expression. For details see https://www.proteinatlas.org/.