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Prediction of the protein stability with online tools.
| Online tools | ARL3: c.91A>G (p.T31A) | ARL3: c.353G>T (p.C118F) |
|---|---|---|
| Mupro | ΔΔG: −0.19 (DECREASE stability) | ΔΔG: −0.23 (DECREASE stability) |
| I-Mutant v2.0 | ΔΔG: −0.50 (Decrease stability) | ΔΔG: −0.13 (Decrease stability) |
ΔΔG: ΔG (mutated protein) –ΔG (wild type protein) in kcal/mol. ΔΔG <0: decrease stability. ΔΔG > 0: increase stability.
