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TNT alleviated oxidative stress and skewed the polarization of macrophages to the M2 phenotype under oxidative stress. Confocal images of M1 and M2 macrophage markers iNOS and CD163 expressed in Mϕs on 2 Ti surfaces under H2O2- (A), LPS- (B), and hyperglycemia- (C) mediated oxidative stress and corresponding semiquantitative analysis (D–F). *p < 0.05, **p < 0.01, ***p < 0.001.
