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. 2021 Mar 4;12:640992. doi: 10.3389/fgene.2021.640992

Table 1.

Top 10 upregulated and 10 downregulated mRNAs between the patients and normal individuals.

Gene symbol Patients expression Normal individuals expression Patients average read count Normal individuals average read count log2 ratio Up/down regulation P-value Q-value
HLA-DRB5 225.835 0.765 3532.39 13.875 7.482495967 up 4.91E-55 1.78E-52
MYBL1 26.42 0.65 1820 51.5 4.544114327 up 8.29E-42 2.47E-39
MYOM2 38.7 1.05 2678.5 78.5 4.529897009 up 1.13E-35 2.32E-33
FOSB 19.76 0.52 1006 29.5 4.506423885 up 2.03E-09 3.04E-08
KLRF1 68.75 2.09 1035 36.5 4.259903293 up 5.50E-25 6.66E-23
CXCL8 42.075 1.37 890 32.5 4.218315485 up 1.28E-11 3.02E-10
G0S2 50.5 1.29 574 20 4.161368474 up 1.36E-08 1.63E-07
RGS1 11.715 0.375 207 8 4.086850386 up 6.25E-10 1.05E-08
RPL36A 262.95 54.965 1548.5 422 4.083172057 up 1.11E-12 3.43E-11
RPL34 1522.475 59.685 9236 422 3.965364098 up 1.23E-11 2.91E-10
ALAS2 1.745 878.28 45.5 26335.5 −9.768604841 down 1.24E-212 4.07E-209
SLC4A1 0.455 82.065 22.5 6477 −8.813880937 down 4.48E-90 2.93E-87
IFI27 0.94 68.11 6 535 −7.096128608 down 2.88E-38 7.25E-36
SLC6A8 0.545 16.94 23.5 984.5 −6.056603232 down 4.39E-37 1.02E-34
PHOSPHO1 6.32 128.8 171 4585 −5.432012286 down 2.61E-17 1.53E-15
SLC25A39 44.395 819.91 1020.5 21348 −5.05753814 down 3.05E-36 6.64E-34
PDZK1IP1 1.49 19.975 15.5 291 −4.951911648 down 5.28E-11 1.11E-09
NLRP6 0.835 13.215 32.5 565.5 −4.679911744 down 1.89E-27 2.95E-25
MMP9 3.01 31.465 93 1361.5 −4.630504037 down 0.006132 0.009425
ALPL 5.28 64.135 182.5 2705.5 −4.580305046 down 9.21E-14 3.34E-12