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. 2021 Mar 4;8:617789. doi: 10.3389/fvets.2021.617789

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Copyright © 2021 Orhan, Juturu, Sahin, Tuzcu, Ozercan, Durmus, Sahin and Sahin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of undenatured type II collagen (UC-II) on the knee joint radiographic and histopathologic findings in monosodium iodoacetate (MIA) induced osteoarthritis rats (n = 7). Representative radiographic (A) and histopathologic (B) images obtained at the end of the experiment are shown. Kellgren-Lawrence and Mankin scores were shown in (C) and (D), respectively. The bars represent the mean and standard deviation of data. Mann-Whitney U test were used to compare the results among different treatment groups. Statistical significance between groups is shown by: ^#P < 0.05 as compared to the MIA group.