Skip to main content
. 2021 Mar 4;13:604119. doi: 10.3389/fnagi.2021.604119

TABLE 2.

Biomarkers with the best discriminating power between AD and non-AD dementia patients.

Biomarker AUC (95% CI) Sensitivity Specificity Total% of predictive accuracy* z-value**
Lumipulse Aβ42 + P-tau 0.915 (0.822–1.000) 91.2% 76.2% 85.5% z = 0.997 vs. Lumipulse Aβ42/40; z = 0.639 vs. Innotest; z = 1.673 vs. Elecsys
Aβ42/40 0.882 (0.785–0.980) 94.1% 71.4% 85.5% z = −0.394 vs. Innotest; z = 0.033 vs. Elecsys
Innotest Aβ42 + P-tau 0.895 (0.801–0.989) 94.1% 76.2% 87.3% z = 0.544 vs. Elecsys
Elecsys Aβ42 + P-tau 0.881 (0.774–0.988) 91.1% 72.2% 84.6%

AUC, Area under the curve.

*The percentage of correct classification of AD + correct classification of non-AD/all cases.

**Values of |z| < 1.96 were taken as evidence that the true ROC areas were not different.