TABLE 2.
Biomarkers with the best discriminating power between AD and non-AD dementia patients.
| Biomarker | AUC (95% CI) | Sensitivity | Specificity | Total% of predictive accuracy* | z-value** | |
| Lumipulse | Aβ42 + P-tau | 0.915 (0.822–1.000) | 91.2% | 76.2% | 85.5% | z = 0.997 vs. Lumipulse Aβ42/40; z = 0.639 vs. Innotest; z = 1.673 vs. Elecsys |
| Aβ42/40 | 0.882 (0.785–0.980) | 94.1% | 71.4% | 85.5% | z = −0.394 vs. Innotest; z = 0.033 vs. Elecsys | |
| Innotest | Aβ42 + P-tau | 0.895 (0.801–0.989) | 94.1% | 76.2% | 87.3% | z = 0.544 vs. Elecsys |
| Elecsys | Aβ42 + P-tau | 0.881 (0.774–0.988) | 91.1% | 72.2% | 84.6% |
AUC, Area under the curve.
*The percentage of correct classification of AD + correct classification of non-AD/all cases.
**Values of |z| < 1.96 were taken as evidence that the true ROC areas were not different.