Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 4;12:619611. doi: 10.3389/fgene.2021.619611

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Qian, Wei, Lu, Sun, Hwang, Jiang, Fu, Zhou, Kong, Zhu, Xiao, Hu and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Interaction network and biological process analysis of the hub genes. (A) Top 10 hub genes screened from the regulatory network. (B) Top 10 hub genes and their first neighbors that are screened from the regulatory network. Hub gene is shown in red to orange on the left. The first neighboring node is shown in blue. The right picture shows the characteristics of the genes in the left picture. The green ones are low-risk genes. The red ones are high-risk genes. The triangles are transcription factors. (C) The biological process analysis of genes in the network was constructed using BiNGO. The color depth of nodes refers to the corrected P value of ontologies. The size of nodes refers to the number of genes that are involved in the ontologies. P < 0.01 was considered statistically significant. (D) The biological process analysis of hub genes was constructed using BiNGO. P < 0.05 was considered statistically significant. (E) Ten-hub-gene enrichment plots from Gene Set Enrichment Analysis (GSEA).