Table 1.

Inclusion criteria for full participation in the Bugs and Brains Study (ie, primary case–control component)

Inclusion criteria	Controls	Depression/anxiety	IBS	Depression/anxiety and IBS
Female sex	✓	✓	✓	✓
Fluent in English	✓	✓	✓	✓
Capacity to provide consent	✓	✓	✓	✓
Live in Melbourne or Geelong (Australia)	✓	✓	✓	✓
Meet DSM-5 criteria for current Depression or Anxiety disorder*	✘	✓	✘	✓
Obessive compulsive disorder, specific phobia, trauma-related or stressor-related disorder, sleep disorder, externalising disorders	✘	–	✘	–
Irritable bowel syndrome (Rome IV)	✘	✘	✓	✓

✓, inclusion criteria; ✘, exclusion criteria (current or lifetime history [as assessed by SCID-5-RV]); -=neither exclusion nor inclusion.

*Specific disorders for inclusion are: major depressive disorder, persistent depressive disorder, social anxiety disorder, panic disorder, agoraphobia and generalised anxiety disorder as assessed by the SCID-5-RV.

DSM-5, Diagnostic and Statistical Manual fifth edition; IBS, irritable bowel syndrome; SCID-5, Structured Clinical Interview for the DSM-5, research version.