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. 2021 Mar 12;7(3):e06444. doi: 10.1016/j.heliyon.2021.e06444

Figure 4.

Figure 4

pGz attenuates LPS effects on cytokine protein expression in mice heart. LPS induced a significant increase in the expression of pro-inflammatory cytokines (TNF-α, NFkB -p65, IL-1β, and IL-6) and anti-inflammatory cytokine (IL-10). pGz pre-treatment (pGz-LPS) at 90 (A) and 360 min (B) significantly decreased expression of TNF-α, NFkB -p65, IL-6 and increases IL-10. pGz post-treatment (LPS-pGz) also significantly reduced expression of TNF-α, NFkB -p65, IL-6, and elevated IL-10 at 90 (C) and 360 min (D) after LPS. Supporting Information File contains uncropped Western Blots. Data are expressed as mean ± SD (∗p < 0.05).