Table 1.

DIRECT ANGIO inclusion and exclusion criteria

Inclusion

Exclusion

Adult ≤75 years Prestroke mRS 0–2 Acute severe neurological deficit at hospital admission confirmed by neurologist defined as:* Unilateral motor deficit with a score ≥5 Facial palsy (item 4 NIHSS 0 to 2) Arm (item 5 NIHSS 0 to 4) Leg (item 6 NIHSS 0 to 4) AND Cortical symptom with a score ≥1 Language (item 9 NIHSS 0 to 3) Extinction (item 11 NIHSS 0 to) Hospital admission ≤5 hours Patients directly admitted to an endovascular-capable centre Immediate availability of the angioroom and endovascular treatment team at the randomisation Affiliation to/beneficiary of a social regime

Severe allergy to contrast agents Pregnant or breastfeeding women Consent refusal or opposition of the relatives Under legal protection Any terminal illness such that patient would not be expected to survive more than 90 days

*New criteria of the version 3.0.

mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.