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. 2021 Mar 17;4(3):e211816. doi: 10.1001/jamanetworkopen.2021.1816

Table 4. Difference-in-Differences Analysis of Racial/Ethnic Disparities in Preterm and Very Preterm Births Among Women Testing Negative for SARS-CoV-2.

Outcome Before pandemic (March 28 to July 31, 2019) Pandemic (March 28 to July 31, 2020) Risk difference before vs during pandemic, % (95% CI)
Denominator Cases, No. Risk, % Denominator Cases, No. Risk, %
Black vs White births
Preterm birth
Non-Latina White 2188 156 7.1 1824 127 7.0 −0.2 (−1.8 to 1.4)
Non-Latina Black 451 65 14.4 445 59 13.3 −1.2 (−5.7 to 3.4)
Difference 7.3 6.3 −1.0 (−5.8 to 3.8)
Adjusted differencea,b −0.9 (−5.8 to 4.0)
Very preterm birth 5124
Non-Latina White 2188 17 0.8 1824 10 0.6 −0.2 (−0.7 to 0.3)
Non-Latina Black 451 20 4.4 445 21 4.7 0.3 (−2.5 to 3.0)
Difference 3.7 4.2 0.5 (−2.3 to 3.3)
Adjusted differencea,b 0.7 (−2.2 to 3.6)
Latina vs White births
Preterm birth
Non-Latina White 2188 156 7.1 1824 127 7.0 −0.2 (−1.8 to 1.4)
Latina 688 74 10.8 600 61 10.2 −0.6 (−3.9 to 2.8)
Difference 3.6 3.2 −0.4 (−4.1 to 3.3)
Adjusted differencea,b −0.6 (−4.4 to 3.1)
Very preterm birth
Non-Latina White 2188 17 0.8 1824 10 0.6 −0.2 (−0.7 to 0.3)
Latina 688 10 1.5 600 9 1.5 0.0 (−1.3 to 1.4)
Difference 0.7 0.9 0.3 (−1.1 to 1.7)
Adjusted differencea,b 0.3 (−1.2 to 1.7)

Abbreviation: SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

a

Adjusted for maternal age (continuous), parity (nulliparous, multiparous), prepregnancy body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) (BMI <25, BMI ≥25), and insurance coverage (Medicaid, private, and other or self-pay); model for Black vs White very preterm birth disparity not adjusted for insurance coverage owing to nonconvergence.

b

Observations with missing covariate values dropped from adjusted analyses (<4% for BMI, <1% all others).