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Modified alginate-based hydrogel loaded with JWH133 promotes osteogenic differentiation in BMSCs. (A) Representative images of ALP staining after 7 days. (B) Representative images of ALP staining after 14 days. (C) Quantification of Alizarin Red S staining. (D) Relative mRNA expression of the osteoblast-specific genes ALP, OPN, and OCN. *P < 0.05 and **P < 0.01 vs the alginate group.
