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. 2021 Mar 4;6(10):6861–6870. doi: 10.1021/acsomega.0c06057

Figure 6.

Figure 6

Modified alginate-based hydrogel loaded with JWH133 suppresses RANKL-induced osteoclastogenesis in vitro. (A) Representative images of TRAP-positive multinuclear cells after 5 days. (B) Representative images of the resorbed area after 7 days. (C,D) Quantification of TRAP-positive multinuclear cells and the area of osteoclasts. (E) Quantification of the resorbed area after 7 days. (F) Relative mRNA expression of osteoclast-specific genes, including ACP5, TRAP, DC-STAMP MMP9, ATP6V0D2, and CTSK. *P < 0.05 and **P < 0.01 vs the alginate group.