Table 2. Concentrations of EDTs and DHDTs in AdA-Rich Rat Tissuesa.
absolute concentrations (pg/g of tissue) |
relative concentrations
(% of analogous ARA metabolite) |
||||||
---|---|---|---|---|---|---|---|
liver | brain | kidney | liver | brain | kidney | ||
7,8-EDT | N/D | N/D | N/D | 7,8-EDT/5,6-EET | N/D | N/D | N/D |
10,11-EDT | 40.6 | N/D | N/D | 10,11-EDT/8,9-EET | 7.03 | N/D | N/D |
13,14-EDT | 47.0 | 18.8 | 8.31 | 13,14-EDT/11,12-EET | 4.73 | 2.67 | 0.55 |
16,17-EDT | 186 | 41.6 | 45.5 | 16,17-EDT/14,15-EET | 31.7 | 8.50 | 3.25 |
7,8-DHDT | N/D | N/D | N/D | 7,8-DHDT/5,6-DHET | N/D | N/D | N/D |
10,11-DHDT | N/D | N/D | 20.9 | 10,11-DHDT/8,9-DHET | N/D | N/D | 0.63 |
13,14-DHDT | 107 | N/D | 16.8 | 13,14-DHDT/11,12-DHET | 0.97 | N/D | 0.94 |
16,17-DHDT | 115 | N/D | 24.3 | 16,17-DHDT/14,15-DHET | 0.66 | N/D | 0.32 |
N/D indicates <LOQ.