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. 2021 Feb 2;15:1753466620981858. doi: 10.1177/1753466620981858

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© The Author(s), 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — ICG001 inhibits transforming growth factor β₁ (TGF-β₁)-induced fibroblast proliferation and transition in CCC-REPF-1 cells. (A) Phase-contrast images of subconfluent CCC-REPF-1 cells (magnification, ×100). (B) Proliferation of CCC-REPF-1 cells, detected using the cell counting kit-8 assay (n = 6). (C) The expression of α-SMA, collagen I (Col I), and collagen III (Col III) in CCC-REPF-1 cells with their corresponding treatments was analyzed by using real-time polymerase chain reaction (n = 6).

The values are expressed as the mean ± standard deviation (SD).

^#p < 0.01, versus the control group.

^*p < 0.01, versus the TGF-β₁ group.

TGF-β₁, transforming growth factor β_1.