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. Author manuscript; available in PMC: 2021 Oct 27.

Published in final edited form as: ACS Nano. 2020 Sep 25;14(10):12732–12748. doi: 10.1021/acsnano.0c03064

Figure 6: — (A) Schematic diagram showing experimental design to test the specificity of TLNP_κ in mixed culture. (B) Confocal microscopic images showing selective uptake of TLNP_κ by human keratinocytes at 4h compared with non-TLN_κ in mixed culture cells (HaCaT: HMEC: BJ-1=1:1:3). K, keratinocyte; F, fibroblasts; E, endothelial cells. Scale; 20 μm. (C) In vitro LDH assay of TLNP_k. (n=10) (D) Live-cell confocal images showing rapid uptake of TLNP_κ by mouse keratinocytes compared to non-TLNP_k. Scale, 10 μm. Indicate movies in the supplement. Data in C were shown as mean ± SEM and were analyzed by one-way ANOVA with the post-hoc Sidak’s multiple comparison test.

Inline graphic — (A) Schematic diagram showing experimental design to test the specificity of TLNP_κ in mixed culture. (B) Confocal microscopic images showing selective uptake of TLNP_κ by human keratinocytes at 4h compared with non-TLN_κ in mixed culture cells (HaCaT: HMEC: BJ-1=1:1:3). K, keratinocyte; F, fibroblasts; E, endothelial cells. Scale; 20 μm. (C) In vitro LDH assay of TLNP_k. (n=10) (D) Live-cell confocal images showing rapid uptake of TLNP_κ by mouse keratinocytes compared to non-TLNP_k. Scale, 10 μm. Indicate movies in the supplement. Data in C were shown as mean ± SEM and were analyzed by one-way ANOVA with the post-hoc Sidak’s multiple comparison test.