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Recombinant IL37 protein does not downregulate early markers of liver fibrogenesis after BDL. Wt mice underwent bile duct ligation. Five microgram rhIL-37 (n = 12) or PBS (n = 14) was i.p. injected prior to BDL and the morning after. Hepatic levels of mRNA were quantified by qPCR after 3 days. Fold changes of mRNA expression were calculated using the ΔΔCt-method normalized to Rpl13a gene expression.
