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. 2021 Mar 4;12:603649. doi: 10.3389/fimmu.2021.603649

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Copyright © 2021 Mountford, Effenberger, Noll-Puchta, Griessmair, Ringleb, Haas, Denk, Reiter, Mayr, Dinarello, Tilg and Bufler.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum levels of IL37 correlates with disease severity in patients with liver cirrhosis. Correlation of CRP (A) and serum IL-37 (B) with CP score in patients with liver cirrhosis compared to healthy control patients. (C) MELD score in patients with cirrhosis compared to healthy controls (MELD in healthy controls was assumed 0). Correlation of serum IL-37 with platelet count (D) and hemoglobin (E) in patients with cirrhosis and healthy controls. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05: according to Spearman correlation or Student's t-test.