Table 3.

Testicular antioxidant/oxidant parameters in the different experimental groups.

Parameter	NC	tBHQ	DOX	tBHQ + DOX
SOD activity (U/mg protein)	2.86 ± 0.34	2.91 ± 0.27	1.08 ± 0.22a	2.13 ± 0.31a,c
CAT activity (U/mg protein)	35.72 ± 3.24	38.76 ± 5.89	10.37 ± 1.42a	34.39 ± 3.16c
GPx activity (U/mg protein)	30.80 ± 2.92	31.35 ± 1.63	8.78 ± 0.68a	28.49 ± 3.23c
GR activity (U/mg protein)	21.05 ± 1.64	21.71 ± 1.77	8.22 ± 0.94a	19.33 ± 1.98c
GSH level (nmol/mg protein)	1.96 ± 0.16	2.18 ± 0.19	0.65 ± 0.13a	2.01 ± 0.10c
TAC (nmol/mg protein)	261.60 ± 17.56	266.00 ± 13.28	81.59 ± 8.17a	232.60 ± 22.04a,c
H2O2 level (µmol/mg protein)	2.01 ± 0.17	1.83 ± 0.21	4.23 ± 0.45a	2.59 ± 0.24a,c
MDA level (nmol/mg protein)	2.92 ± 0.24	2.47 ± 0.35	18.32 ± 1.02a	7.41 ± 0.63a,c

Values are mean ± SD, n = 6/group. NC: normal control, tBHQ: tert-butylhydroquinone, DOX: doxorubicin.

^ap < 0.05 versus NC group, ^cp < 0.05 versus DOX group (One-way ANOVA with Tukey’s post-hoc test).