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. 2021 Mar 10;11:5593. doi: 10.1038/s41598-021-85092-x

Figure 2.

Figure 2

Developmental changes to PV and PNN populations within frontal cortical subregions. Mice in the adult cohort had significantly greater numbers of (A,B) PV+ neurons and (C,D) PNNs in the PrL and IL PFC, however no age differences were observed in the OFC. There were significantly more PV/PNN colocalised neurons in the adult cohort (E,F) in the IL. Data were assessed using two-way ANOVAs *p < 0.05, **p < 0.01. Representative photomicrographs were taken at 40X magnification (red—parvalbumin, green—WFA + PNN), scale bars show 100 μm.