Table 1.

Demographic, genotype and clinical data show as mean (standard deviation) unless otherwise noted.

	Chemotherapy N = 42	Chemotherapy naive N = 41	Healthy control N = 53
Age	55 (7)	59 (7)*	55 (9)
Age range	43–73	41–74	41–71
Education (yr)	16 (3)	17 (2)	17 (3)
Breast radiation	73%	65%
Endocrine therapy (tamoxifen)	43%	58%
Disease stage at diagnosis (0, I, II, III)	0%, 26%, 55%, 19%	37%*, 50%*, 13%*, 0%*
Time since primary treatment (yr)	4.8 (4.8)	6.5 (5.6)
Postmenopausal	89%	82%	44%*
Clinical assessment of depression score	51 (11)*	44 (10)	44 (9)
APOE e4	31%	24%	23%
BDNF Met	43%	28%	36%
MDR1 T	81%	78%	83%
GST Null	38%	42%	51%
COMT Val	88%	91%	95%

*Denotes significant (p < 0.05) difference.