Extended Figure 3: Continuous activation under hypoxia results in enrichment of genes related to terminal exhaustion and repression of genes from more progenitor-like exhausted cells.
a, Heatmap of selected genes from Fig. 3d (genes specifically enriched in progenitor exhausted T cells) from all four in vitro conditions detailed in Fig. 2. Each group n=3 b, Heatmap of selected genes from Fig. 3e (genes specifically enriched in terminally exhausted T cells) from all four in vitro conditions detailed in Fig. 2. Each group n=3.