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. 2021 Mar 2;12:20. doi: 10.1186/s13229-021-00427-9

Table 5.

Zero-order and partial correlations between TAS-8 latent trait scores and other clinical measures in SPARK sample

Covariate r [95% CrI] BFROPE P(ROPE|Data) rp [95% CrI] BFROPE P(ROPE|Data)
SRS-2 0.642 [0.598, 0.686] 2.07 × 1020 < 0.001 0.514 [0.458, 0.567] 3.74 × 1018 < 0.001
RBS-R SM 0.385 [0.322, 0.444] 9.83 × 106 < 0.001 0.294 [0.225, 0.363] 9.05 × 104 < 0.001
RBS-R RS 0.432 [0.372, 0.494] 1.25 × 107 < 0.001 0.297 [0.228, 0.362] 1.68 × 105 < 0.001
BDI-II 0.420 [0.358, 0.480] 1.28 × 107 < 0.001 0.159 [0.086, 0.232] 3.34 0.059
GAD-7 0.423 [0.360, 0.481] 1.34 × 107 < 0.001 0.150 [0.082, 0.222] 2.18 0.087
BFNE-S 0.358 [0.292, 0.423] 3.21 × 104 < 0.001 0.105 [0.030, 0.180] 0.258 0.446
PHQ-15 0.275 [0.208, 0.346] 23 0.019 0.093 [0.019, 0.165] 0.150 0.579
ASQoL − 0.442 [− 0.503, − 0.385] 2.28 × 107 < 0.001 − 0.259 [− 0.328, − 0.189] 3.86 × 103 < 0.001
Suicidality 0.303 [0.222, 0.382] 19 0.009 0.111 [0.021, 0.198] 0.124 0.403
IPIP-N10 0.475 [0.416, 0.531] 9.90 × 109 < 0.001

All partial correlations (rp) control for neuroticism (IPIP-N10 scores) when examining the correlation between TAS-8 scores and other variables of interest. Bayes factors indicating substantial evidence against the interval null hypothesis (i.e., r or lies within [− 0.2, 0.2] or rp lies within [− 0.1, 0.1]) are presented in bold, whereas Bayes factors indicating substantial evidence for the interval null hypothesis are presented in italics. Correlations are estimated using Bayesian methods and are presented along with 95% highest density credible intervals (CrI)

BFROPE, Bayes factor assessing interval null hypothesis that the effect falls within the region of practical equivalence (ROPE); P(ROPE|Data), proportion of the r/rp posterior distribution falling within the ROPE, conditioned on the observed data (i.e., probability that the interval null hypothesis is true); SRS-2, Social Responsiveness Scale-Second Edition; RBS-R, Repetitive Behavior Scale-Revised; SM, sensory motor (“lower order” repetitive behaviors) subscale; RS, ritualistic/sameness (“higher order” repetitive behaviors) subscale; BDI-II, Beck Depression Inventory-II; GAD-7, Generalized Anxiety Disorder-7; BFNE-S, Brief Fear of Negative Evaluation-Short; PHQ-15, (modified) Patient Health Questionnaire-15; ASQoL, Autism Spectrum Quality of Life; Suicidality, BDI-II item 9 (Suicidal Thoughts or Wishes); IPIP-N10, ten-item neuroticism scale from the international personality item pool