Figure 1.
The cytotoxicity of Phy in breast cancer cells. (A) Phy suppressed the cell viability of MCF-7 cells measured by MTT assay after 24 h exposure. (B) Phy enhanced the release of LDH in MCF-7 cells. Twenty-four hour Phy incubation enhanced the activities of (C) caspase-3, (D) caspase-8, and (E) caspase-9 in MCF-7 cells. (F) Phy enhanced the apoptosis rate of MCF-7 cells after 24 h exposure. Data are expressed as percentages relative to the corresponding control cells and as mean ± S.D. (n = 6). *p<0.05, **p<0.01, and ***p<0.001 versus control cells.