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. 2020 Dec 27;22(3):727–739. doi: 10.1093/pm/pnaa396

Table 2.

Primary conditions and symptoms of 1,145 participants and comparison of cannabis-naive with non-naive participants

Variable All (N=1,145) Naive (n=691) Non-Naive (n=438) P Value
Primary illness or medical condition you currently treat with medical cannabis n (%) n (%) n (%)
 Unknown 1 1 0
 Anxiety disorder 109 (9.5) 31 (4.5) 74 (16.9) <0.001
 Arthritis 81 (7.1) 53 (7.7) 27 (6.2) 0.333
 Brain injury 3 (0.3) 3 (0.4) 0 (0.0) 0.287
 Cancer or leukemia 17 (1.5) 10 (1.4) 7 (1.6) 0.841
 Chronic pain 787 (68.8) 523 (75.8) 257 (58.7) <0.001
 Crohn’s disease 6 (0.5) 2 (0.3) 4 (0.9) 0.215
 Diabetes 2 (0.2) 2 (0.3) 0 (0.0) 0.525
 Eating disorder 2 (0.2) 0 (0.0) 2 (0.5) 0.151
 Epilepsy 5 (0.4) 4 (0.6) 1 (0.2) 0.654
 Gastrointestinal disorder 6 (0.5) 2 (0.3) 4 (0.9) 0.215
 Headache 25 (2.2) 15 (2.2) 10 (2.3) 0.903
 Insomnia 57 (5.0) 26 (3.8) 28 (6.4) 0.044
 Movement disorder 9 (0.8) 9 (1.3) 0 (0.0) 0.016
 Osteoporosis 1 (0.1) 0 (0.0) 1 (0.2) 0.388
 Psychiatric or mental health disorder 4 (0.3) 1 (0.1) 3 (0.7) 0.305
 PTSD 8 (0.7) 2 (0.3) 6 (1.4) 0.062
 Seizures 1 (0.1) 1 (0.1) 0 (0.0) 1.000
 Other 21 (1.8) 6 (0.9) 14 (3.2) 0.004
Primary symptoms you currently treat with medical cannabis
 Anxiety 327 (28.6) 124 (17.9) 189 (43.2) <0.001
 Appetite loss 105 (9.2) 24 (3.5) 79 (18.0) <0.001
 Chronic pain 915 (79.9) 581 (84.1) 325 (74.2) <0.001
 Depression 219 (19.1) 82 (11.9) 129 (29.5) <0.001
 Gastrointestinal disorder 60 (5.2) 26 (3.8) 32 (7.3) 0.009
 Headache 166 (14.5) 67 (9.7) 98 (22.4) <0.001
 Insomnia 384 (33.5) 189 (27.4) 189 (43.2) <0.001
 Intraocular eye pressure 14 (1.2) 11 (1.6) 3 (0.7) 0.180
 Memory loss 43 (3.8) 22 (3.2) 17 (3.9) 0.532
 Nausea 95 (8.3) 33 (4.8) 60 (13.7) <0.001
 Seizures 11 (1.0) 6 (0.9) 5 (1.1) 0.649
 Spasms 118 (10.3) 76 (11.0) 39 (8.9) 0.257
 Stress 219 (19.1) 75 (10.9) 133 (30.4) <0.001
 Other 24 (2.1) 12 (1.7) 12 (2.7) 0.255

PTSD = posttraumatic stress disorder.