Table 1. List of major constructs used in the text.
Construct # | Description | Modality |
---|---|---|
254 | CAR sequence targeting CD19 | Anti-CD19 CAR |
340 | Stabilized CD19 ECD–anti-Her2 | Purified BP |
374 | Sequence of 254 –P2A –sequence of 340 | Anti-CD19 CAR + stabilized BP |
390 | CAR sequence targeting Her2 | Anti-Her2 CAR |
460 | Anti-Her2 –stabilized CD19 ECD–anti-EGFR | Purified BP |
Constructs are presented in the numerical order with a description of the encoded sequences in column 2 and the format in which the expressed sequence is utilized in column 3. The long dashes indicate a linker sequence. P2A refers to a cleavage sequence. BP refers to a bridging protein.