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. 2021 Mar 18;16(3):e0248716. doi: 10.1371/journal.pone.0248716

Table 2. Clinical and medical history of patients with coronary artery disease depending on the degree of coronary lesion.

Parameter Group 1 n = 39 Group 2 n = 20 Group 3 n = 25 P
Men, n (%) 27 (69.23) 17 (85.0) 19 (76.0)
Age, median (range), years 64.1 (60.0;66.5) 65.2 (43.0;56.2) 65.1 (61.0;68.2)
BMI, median (range), kg/m2 29.42 (29.15;30.22) 26.33 (25.21;27.44) 29.41 (29.29;31.68)
Excess body weight, n (%) 15 (38.5) 3 (15.0) 10 (40.0) P1,2 = 0.001
P1,3 = 0.011
P 2,3 = 0.003
Arterial hypertension, n (%) 36 (92.30) 20 (100) 25 (100)
Hypercholesterolemia, n (%) 10 (25.62) 4 (20) 6 (24)
Smoking, n (%) 26 (66.67) 19 (95) 13 (52) P 1,2 = 0.011
P 2,3 = 0.013
Anamnesis
Family history of CAD, n (%) 19 (48.75) 14 (70) 16 (64) P 1,2 = 0.023
P 1,3 = 0.014
Clinic of angina before the development of MI, n (%) 36 (92.31) 17 (85) 21 (84)
Family history of CAD, n (%) 21 (53.85) 14 (70) 22 (88) P 1,2 = 0.023
P 1,3 = 0.024
History of stroke, n (%) 0 6 (30) 0
CHF, n (%) 30 (76.92) 20 (100) 16 (64) P 1,2 = 0.023
P 2,3 = 0.021
Atherosclerosis of the 1st CA, n (%) 3 (7.74) 3 (15) 0
Atherosclerosis of the 2nd CA, n (%) 0 4 (20) 0 P 1,2 = 0.015
Atherosclerosis of three or more CA, n (%) 36 (92.33) 13 (65) 25 (100)
Atherosclerosis of other pools, n (%) 6 (15.42) 3 (15) 4 (16) P 2,3 = 0.021
Ejection fraction, median (range), % 55 (45.0;57.0) 52 (48.0;55.0) 46 (38.0;56.0)
Creatinine, median (range), mmol/L 83.5 (62.4;99.1) 94.74 (73.3;119.7) 101.47 (87.5;145.5) P 1,3 = 0.001

Note: P—level of statistical significance; P 1,2 –Groups 1 and 2; P 1,3 –Groups 1 and 3. Abbreviations: CA–coronary artery; CAD–coronary artery disease; CHF–chronic heart failure; BMI–body mass index; MI–myocardial infarction.