Table 4. The concentration of adiponectin, leptin and IL-6 in the culture medium of epicardial and perivascular adipocytes, depending on the degree of coronary lesion.
| Parameter | Adipocyte localization | Group 1 n = 39 | Group 2 n = 20 | Group 3 n = 25 | P | |
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | ||||
| Adiponectin, ng/ml | EAТ | а | 12.36 (10.21;13.84) | 10.47 (7.89;12.18) | 8.10 (5.62;10.33) | P1.2 = 0.022 |
| P1.3 = 0.001 | ||||||
| PVAТ | b | 11.25 (9.21;14.55) | 9.38 (8.14;12.00) | 9.23 (857;11.83) | P1a.1b = 0.002 | |
| P2a.2b = 0.0014 | ||||||
| P3a.3b = 0.003 | ||||||
| P1.2 = 0.0011 | ||||||
| P1.3 = 0.007 | ||||||
| Leptin, ng/ml | EAТ | а | 5.61 (3.95;7.00) | 8.67 (6.35;9.92) | 5.77 (3.98;7.17) | P1.2 = 0.032 |
| P2.3 = 0.0013 | ||||||
| PVAТ | b | 3.96 (3.26;4.98) | 7.95 (3.69;8.81) | 6.96 (5.26;7.98) | P2a.2b = 0.001 | |
| P1.3 = 0.0032 | ||||||
| IL-6, pg/ml | EAТ | а | 15.92 (13.22;20.16) | 28.17 (25.31;33.69) | 30.77 (20.10;37.97) | P1.2 = 0.0041 |
| P1.3 = 0.022 | ||||||
| PVAТ | b | 8.33 (5.45;10.01) | 16.92 (13.37;20.19) | 15.53 (13.05;19.64) | P1.2 = 0.0023 | |
| P1.3 = 0.0012 | ||||||
Note: P—level of statistical significance; P 1,2 –Groups 1 and 2; P 1,3 –Groups 1 and 3. Abbreviations: EAT–epicardial adipose tissue; IL-6 –interleukin-6; PVAT–perivascular adipose tissue.