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. 2021 Mar 18;16(3):e0245075. doi: 10.1371/journal.pone.0245075

Table 2. Disease-free survival and disease-specific survival according to SLC2A1 expression in 279 patients with gastric cancer (Eulji Hospital cohort).

Disease-free survival Univariate1 Multivariate2 HR 95% CI
 SLC2A1 (low vs. high) 0.041 0.283 0.689 0.350 1.359
 T stage (1 or 2 vs. 3 or 4) <0.001 0.088 2.167 0.892 5.268
 N stage (0 vs. 1, 2 or 3) <0.001 <0.001 6.950 2.707 17.843
 Histological grade (1 or 2 vs. 3) 0.442 0.111 0.596 0.315 1.126
 Vascular invasion (absence vs. presence) <0.001 0.005 2.451 1.303 4.612
 Perineural invasion (absence vs. presence) <0.001 0.087 1.756 0.922 3.345
Disease-specific survival Univariate1 Multivariate2 HR 95% CI
 SLC2A1 (low vs. high) <0.001 0.005 2.543 1.330 4.865
 T stage (1 or 2 vs. 3 or 4) <0.001 0.025 2.535 1.125 5.713
 N stage (0 vs. 1, 2 or 3) <0.001 0.02 2.438 1.151 5.163
 Histological grade (1 or 2 vs. 3) 0.145 0.536 1.194 0.682 2.089
 Vascular invasion (absence vs. presence) <0.001 0.362 1.320 0.727 2.397
 Perineural invasion (absence vs. presence) <0.001 0.369 1.316 0.723 2.395

HR, hazard ratio; CI, confidence interval.

1Log rank test.

2Cox proportional hazard model.

p < 0.05 is shown in bold.