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. 2021 Mar 18;16(3):e0248868. doi: 10.1371/journal.pone.0248868

Table 5. Patient characteristics by cohort.

Derivation Cohort (110) Validation Cohort (83) p
Age, years** 67 (50–77) 62 (48–72) 0.08
Male n (%)*§ 62 (56) 43 (52) 0.561
APACHE II score, points** 17 (13–21) 23.5 (17–29) 0.000
Admission Diagnosis n (%)*§§
 Respiratory Disease 30 (27) 15 (18) 0.277
 Post Surgery 23 (21) 24 (29)
 Sepsis or Septic Shock 17 (15) 9 (11)
 Trauma 13 (12) 9 (11)
 Neurologic Disease 12 (11) 12 (14)
 Cardiac Disease 3 (3) 7 (8)
 Others 12 (11) 7 (8)
Days of Mechanical Ventilation, days** 5 (2–7) 5 (2.5–8.5) 0.182

*presented as absolute and relative frequency.

**presented as median and interquartile range and applied Mann-Whitney U test.

§ Fisher Exact test.

§§ Chi-square test.