Table 1. Genes encoding UDP-GlcNAc: PI α1–6 GlcNAc-transferase (GPI GnT) complex subunits in mammalian cells, yeast and T. brucei.
Mammalian gene | Yeast gene | T. brucei gene (TriTrypDB gene ID) | Calculated MW of T. brucei gene product | Rank in TbGPI3-3Myc pull-downs1 | Rank in total T. brucei cell Proteome2 |
---|---|---|---|---|---|
PIGA | GPI3 | TbGPI3 (Tb927.2.1780) | 51.6 kDa | 1 | 6475 |
PIGH | GPI15 | TbGPI15 (Tb927.5.3680) | 28.8 kDa | 2 | 7038 |
PIGP | GPI19 | TbGPI19 (Tb927.10.10110) | 16.5 kDa | 3 | 6185 |
PIGC | GPI2 | TbGPI2 (Tb927.10.6140) | 38.5 kDa | 4 | 6798 |
PIGQ | GPI1 | TbGPI1 (Tb927.3.4570) | 81.5 kDa | 5 | 5285 |
TbArv1 (Tb927.3.2480) | 28.7 kDa | 6 | 7149 | ||
PIGY | ERI1 | TbERI1 (Tb927.4.780) | 10.1 kDa | 7 | 7149 |
TbUbCE (Tb927.2.2460) | 22.6 kDa | 8 | 2538 | ||
DPM2 | - | TbDPM2 (Tb927.9.6440)3 | 9.3 kDa | not present | 7149 |