Table 1.
Comparison of preoperative and postoperative clinical state [M (IQR)]
| Time | Medication off | Medication on | |||||
|---|---|---|---|---|---|---|---|
| UPDRS-III (0 ~ 108) | BBS (0 ~ 56) | UPDRS-III (0 ~ 108) | BBS (0 ~ 56) | LEDD (mg) | PDQ-39 (0 ~ 124) | FOG-Q | |
| Preoperative | 60.0 (23) | 44 (11) | 26.2 (23) | 52 (7) | 831 (453) | 49 (38) | 14 (12) |
| Postoperative | |||||||
| 1 month | 35.0 (22) | 48 (11) | 15.0 (16) | 53 (5) | – | – | 9 (12) |
| 3 month | 31.5 (12) | 48 (10) | 13.0 (13) | 53 (5) | 550 (357.5) | 34 (25) | 9 (12) |
| 6 month | 31.0 (17) | 48 (12) | 12.0 (11) | 54 (5) | 475 (220.5) | 23 (20) | 9 (10) |
| Total P | <0.001 | 0.084 | <0.001 | 0.058 | <0.001 | <0.001 | 0.068 |
| χ2 | 109.966 | 35.705 | 74.042 | 29.351 | 62.000 | 104.246 | 7.131 |
| P1 | <0.001 | – | <0.001 | – | – | – | – |
| P2 | <0.001 | – | <0.001 | – | < 0.010 | < 0.010 | – |
| P3 | <0.001 | – | <0.001 | – | < 0.010 | < 0.010 | – |
P1 value is the result of comparison between 1 month and preoperative, P2 value is the result of comparison between 3 months and preoperative, P3 value is the result of comparison between 6 months and preoperative; STN-DBS Subthalamic nucleus - deep brain stimulation, UPDRS-III Unified Parkinson’s Disease Rating ScaleIII, BBS Berg Balance Scale, LEDD Levodopa equivalent dose, PDQ-39 39-Item Parkinson’s Disease Questionnaire, FOG-Q Freeze of gait questionnaire; except LEDD unit is mg, all other index units are points