Table 1 |.
Genome-wide significant (P < 5 × 10−8) findings using linear regression with lead SNPs for EUR PCL-Total and sub-phenotype GWAS analyses (n = 186,689 individuals)
| PCL-Total | LD independent lead SNP | Chr | Effect allele | Beta | P | INFO score | SNP location | Nearest gene |
| rs542933551 | 17 | AAAAACAAAAC | 0.4585 | 2.02E-13 | 0.95 | 43557054 | PLEKHM1 | |
| rs10235664 | 7 | C | −0.3667 | 1.82E-11 | 0.93 | 2086814 | MAD1L1 | |
| rs35761884 | 1 | C | −0.3076 | 3.46E-10 | 0.92 | 73787732 | LINC01360 | |
| rs111488606 | 3 | CA | 0.3102 | 1.72E-09 | 0.83 | 49864924 | TRAIP | |
| rs13262595 | 8 | G | −0.2823 | 2.20E-09 | 1.00 | 143316970 | TSNARE1 | |
| rs2314662 | 19 | C | −0.3614 | 3.78E-09 | 0.93 | 18702515 | C19orf60 | |
| rs10171148 | 2 | A | 0.2811 | 5.87E-09 | 0.96 | 22466171 | LOC102723362 | |
| rs62465629 | 7 | C | −0.3929 | 6.30E-09 | 0.85 | 110153866 | IMMP2L | |
| rs1496246 | 11 | G | 0.2973 | 6.60E-09 | 0.90 | 133548061 | OPCML | |
| rs251350 | 5 | C | −0.2538 | 1.03E-08 | 1.12 | 140225137 | PCDHA1 | |
| rs11507683 | 9 | T | 0.4137 | 1.15E-08 | 0.96 | 140262424 | EXD3 | |
| rs599550 | 18 | A | 0.3948 | 1.18E-08 | 0.95 | 53252388 | TCF4 | |
| rs4364183 | 3 | A | 0.3043 | 1.22E-08 | 0.93 | 18809536 | SATB1-AS1 | |
| rs62417832 | 6 | T | 0.2922 | 2.90E-08 | 1.00 | 88640221 | SPACA1 | |
| rs111950471 | 5 | TATTA | −0.2769 | 4.34E-08 | 0.98 | 107450098 | FBXL17 | |
| Re-experiencing | LD independent lead SNP | Chr | Effect allele | Beta | P | INFO score | SNP location | Nearest gene |
| rs35371867 | 18 | A | 0.1006 | 1.24E-10 | 0.97 | 53193027 | TCF4 | |
| rs2777888 | 3 | G | 0.0929 | 2.26E-10 | 0.98 | 49898000 | CAMKV | |
| rs10235664 | 7 | C | −0.1055 | 4.66E-10 | 0.93 | 2086814 | MAD1L1 | |
| rs242925 | 17 | T | −0.0931 | 5.50E-10 | 0.94 | 43888866 | CRHR1 | |
| rs139356208 | 11 | CACAAAACAAA | −0.0897 | 9.63E-09 | 0.90 | 28631779 | RASEF | |
| rs1501485 | 1 | G | −0.0839 | 1.22E-08 | 0.97 | 73995259 | LRRIQ3 | |
| rs11773880 | 7 | G | −0.0977 | 1.97E-08 | 0.93 | 106540171 | PIK3CG | |
| rs34177209 | 19 | A | 0.1205 | 2.34E-08 | 0.62 | 18474978 | PGPEP1 | |
| rs10977193 | 9 | A | −0.0934 | 4.17E-08 | 0.96 | 8542019 | PTPRD | |
| Avoid-ance | LD independent lead SNP | Chr | Effect allele | Beta | P | INFO score | SNP location | Nearest gene |
| rs55925547 | 17 | C | 0.1932 | 2.08E-13 | 0.98 | 43556807 | PLEKHM1 | |
| rs199913382 | 17 | C | 0.1772 | 1.05E-12 | 0.98 | 44625866 | LRRC37A2 | |
| rs35761884 | 1 | C | −0.1388 | 9.72E-11 | 0.92 | 73787732 | LINC01360 | |
| rs251350 | 5 | C | −0.1192 | 8.15E-10 | 1.12 | 140225137 | PCDHA1 | |
| rs4129585 | 8 | C | −0.125 | 1.25E-09 | 1.00 | 143312933 | TSNARE1 | |
| rs2314662 | 19 | C | −0.1599 | 2.74E-09 | 0.93 | 18702515 | C19orf60 | |
| rs62465629 | 7 | C | −0.175 | 3.54E-09 | 0.85 | 110153866 | IMMP2L | |
| rs62417832 | 6 | T | 0.1335 | 7.04E-09 | 1.00 | 88640221 | SPACA1 | |
| rs11507683 | 9 | T | 0.1834 | 7.74E-09 | 0.96 | 140262424 | EXD3 | |
| rs10171148 | 2 | A | 0.1211 | 1.07E-08 | 0.96 | 22466171 | LOC102723362 | |
| rs10235664 | 7 | C | −0.1337 | 2.17E-08 | 0.93 | 2086814 | MAD1L1 | |
| rs1496246 | 11 | G | 0.1234 | 3.66E-08 | 0.90 | 133548061 | OPCML | |
| Hyper-arousal | LD independent lead SNP | Chr | Effect allele | Beta | P | INFO score | SNP location | Nearest gene |
| rs377112142 | 17 | CT | 0.1323 | 3.06E-13 | 0.84 | 43663455 | MAPK8IP1P2 | |
| rs55789728 | 7 | G | −0.1303 | 4.62E-13 | 0.93 | 2107649 | MAD1L1 | |
| rs576430065 | 9 | CA | −0.1206 | 1.67E-11 | 0.78 | 96373697 | PHF2 | |
| rs140288713 | 17 | A | 0.1286 | 3.11E-11 | 0.90 | 44690708 | NSFP1 | |
| rs1496246 | 11 | G | 0.1037 | 1.77E-10 | 0.90 | 133548061 | OPCML | |
| rs547649546 | 3 | CA | −0.0937 | 1.59E-09 | 0.91 | 49789921 | IP6K1 | |
| rs2887882 | 1 | T | −0.1118 | 1.89E-09 | 0.98 | 113170389 | CAPZA1 | |
| rs7519147 | 1 | T | −0.0906 | 1.90E-09 | 0.96 | 73994416 | LRRIQ3 | |
| rs13032994 | 2 | C | −0.0968 | 3.73E-09 | 1.00 | 52709559 | NRXN1 | |
| rs113341106 | 7 | GC | 0.0923 | 3.82E-09 | 0.93 | 114039998 | FOXP2 | |
| rs12420134 | 11 | G | 0.1229 | 6.45E-09 | 0.87 | 16260861 | SOX6 | |
| rs17209774 | 9 | C | −0.0907 | 7.97E-09 | 0.97 | 4145163 | GLIS3 | |
| rs60958094 | 14 | T | 0.0961 | 1.99E-08 | 0.81 | 54711168 | CDKN3 | |
| rs4129585 | 8 | C | −0.0835 | 2.07E-08 | 1.00 | 143312933 | TSNARE1 | |
| rs549326362 | 5 | T | −0.0884 | 4.46E-08 | 0.94 | 107444481 | FBXL17 | |