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. 2021 Mar 19;418:129392. doi: 10.1016/j.cej.2021.129392

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Fig. 1 — (a) Schematic diagram of inhalable bionic-virus nanovaccine activating cellular immunity and humoral immunity of respiratory mucosa. (b) TEM images of bionic-virus particles. Scale bars, 200 nm. (c) Coomassie blue staining results of RBD protein. (d) The concentration of protein in the supernatant of the solution is detected by nanodrop. (e) The fluorophore-labeled RBD in free or particulate form binds to HEK-293T cells expressing hACE2. (f) The stability of bionic-virus particles in PBS at different temperatures, pH = 7.0, 0.2 mg/mL, PDI = 12–18%. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)