Table 5.
Sensitivity, specificity, positive predictive values (PPV), negative predictive values (NPV) when combined various fecal calprotectin thresholds with either low serum albumin or high platelet count were used in diagnosing IBD.
| Fecal calprotectin threshold and (low albumin or high platelet count) | n | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV, % (95% CI) | NPV, % (95% CI) |
|---|---|---|---|---|---|
| >50 μg/g | 92 | 67.9 (54.5–78.9) | 97.4 (86.8–99.9) | 97.3 (86.2–99.9) | 69.1 (56.0–79.7) |
| >100 μg/g | 92 | 66.0 (52.6–77.3) | 100 (91.0–100) | 100|| (90.1–100) | 68.4 (55.5–79.0) |
| >150 μg/g | 92 | 64.2 (50.7–75.7) | 100 (91.0–100) | 100 (89.9–100) | 67.2 (54.4–77.9) |
| >200 μg/g | 92 | 60.4 (46.9–72.4) | 100 (91.0–100) | 100 (89.3–100) | 65.0 (52.4–75.8) |
| >250 μg/g | 92 | 60.4 (46.9–72.4) | 100 (91.0–100) | 100 (89.3–100) | 65.2 (52.4–75.8) |
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Odds ratio was infinity (95% CI 18.4-infinity), p < 0.0001 likelihood of having IBD.
CI, confident interval; n, sample size.