FIGURE 1.

Transfer process of engineered S. cerevisiae in the synthesis of plant natural products. The brown circle with black arrow indicates substrate transferred into the cells. The green square with black arrow indicates the product transferred out of the cell. The blue arrow indicates intermediates transferred in cell. The circles around the cell represent different strategies to refine the metabolic mass transfer in S. cerevisiae. Blue circles represent strategies to enhance intracellular mass transfer process. Pink circles represent strategies to enhance trans-plasma membrane mass transfer process.