Table 1.
Patient characteristics according to prednisolone response in B-ALL.
| Baseline characteristics | Prednisolone good responders n (%) |
Prednisolone poor responders n (%) |
P value |
|---|---|---|---|
| Number of patients | 120 | 28 | |
| Age at diagnosis (in years) | 0.82 | ||
| 1–9 | 85 (70.8) | 21 (75) | |
| ≥10 | 35 (29.2) | 7 (25) | |
| Sex | 0.13 | ||
| Male | 75 (62.5) | 22 (78.6) | |
| Female | 45 (37.5) | 6 (21.4) | |
| TLC at diagnosis (X109/L) | 0.067 | ||
| <50 | 90 (75) | 16 (57.1) | |
| ≥50 | 30 (25) | 12 (42.9) | |
| NCI risk | 0.41 | ||
| Standard risk | 54 (45) | 10 (35.7) | |
| High risk | 66 (55) | 18 (64.3) | |
| Cytogenetics | 0.68 | ||
| BCR-ABL1 | 6 (5) | 1 (3.6) | |
| E2A-PBX1 | 6 (5) | 1 (3.6) | |
| ETV6-RUNX1 | 9 (7.5) | 1 (3.6) | |
| MLL-rearranged | 0 | 0 | |
| Hyperdiploid | 14 (11.7) | 2 (7.1) | |
| Hypodiploid | 3 (2.5) | 0 | |
| B-others | 71 (59.2) | 22 (78.6) | |
| Not available | 11 (9.2) | 1 (3.6) | |
| BM remission | 0.15 | ||
| Yes | 114 (95.8) | 23 (88.5) | |
| No | 5 (4.2) | 3 (11.5) | |
| Post-induction MRD | 0.62 | ||
| Negative | 93 (78.2) | 23 (84.6) | |
| Positive | 23 (19.3) | 4 (15.4) | |
| Inevaluable | 3 (2.5) | 0 |