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. 2021 Mar 5;11:553594. doi: 10.3389/fonc.2021.553594

Figure 4.

Figure 4

Risk score analysis of the GBM exo-lncRNA signature in the training set from TCGA and validation set from CGGA. (A–C) Analysis performed using the training set from TCGA; (D–F) CGGA validation set analysis. (A, D) Kaplan-Meier survival curve of high-risk and low-risk groups. The table below shows the number of patients at risk at different time points. (B, E) Time‐dependent ROC curves based on risk score level. (C, F) Risk score analysis of the GBM exo-lncRNA signature. Upper panel: patient survival status and time distributed by risk score. Middle panel: risk score curve of the exo-lncRNA signature. Bottom panel: heatmap of SOX21-AS1, HOTAIR, and STEAP3-AS1 expression in GBM samples. The colors from red to green indicate expression level from high to low. The dotted line indicates the individual inflection point of the risk score curve, by which the patients were categorized into low-risk and high-risk groups. ROC: receiver operating characteristic.